The Barrett’s Oesophagus Registry, is an essential database that was established in 2009 to meet our aim of combating Oesophageal Adenocarcinoma (OAC) through early detection. To date, over €1.6 million in Lollipop Day funding has gone towards keeping the Registry alive, employing five full-time Registry personnel and linking five national hospitals: St. James’s, St. Vincent’s, Beaumont, Mater Misericordiae, Dublin and Mercy Hospital, Cork.
Since 2009 over 6,500 patients have been recorded on the Barrett’s Registry. Though not cancerous, Barrett’s Oesophagus is a condition that is frequently a precursor to full-scale Oesophageal Cancer. The Registry helps the medical professionals identify at-risk patients earlier and track their progress using endoscopies and bioscopies. Cellular changes such as dysplasia and or cancer can be diagnosed much earlier, meaning Oesophageal Cancer can be addressed in its early and most treatable phase.
The data manager records and monitors a range of follow-up data for all Registry patients across all five hospital sites. Barrett’s patients who show progression in their disease are offered Radio Frequency Ablation (RFA) therapy, a highly effective Halo procedure that eradicates diseased tissue and allows healthy new tissue to regenerate.
The Barrett’s Oesophagus Registry is now part of the UK Radio Frequency Ablation Registry that covers 26 hospitals of which St. James’s Hospital Dublin is the third largest contributing centre.
OCF donations also fund a National Barrett’s Bio Bank that operates in tandem with the National Barrett’s Registry. Tissue and blood samples from consenting Barretts patients are collected, stored and used for vital patient-focused research that is helping medical professionals to better understand what factors drive progression to Oesophageal Cancer. Three scientific studies which have utilised this national biobank have been submitted for publication and are currently under review.
Thanks to your funding, scientists can now draw upon this invaluable collection in excess of 800 tissue and more than 600 blood samples collected at St. James’s and Beaumont hospitals.
However, given the impact of Covid-19 restrictions on our fundraising this year, we have not reached the goal required to continue funding this programme and are seeking your support through the 5050OCF campaign to raise €150k that will allow us to continue funding this crucial, life-saving service.